Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699398 | 1.00 | LMNA (0.45) | LMNASMN1; SMN2CA1CA2ACHE | |
| SCHEMBL23699049 | 0.84 | LMNA (0.50) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL23699046 | 0.84 | LMNA (0.50) | LMNASMN1; SMN2CTSKCTSSCTSL | |
| SCHEMBL23699409 | 0.82 | SYK (0.44) | CTSKCTSSCTSLSYKCTSB | |
| SCHEMBL23699411 | 0.82 | SYK (0.44) | CTSKCTSSCTSLSYKCTSB | |
| SCHEMBL23699392 | 0.81 | CNR2 (0.44) | LMNASMN1; SMN2L3MBTL1CTSKCTSS | |
| SCHEMBL23699389 | 0.81 | CNR2 (0.44) | LMNASMN1; SMN2L3MBTL1CTSKCTSS | |
| SCHEMBL22636138 | 0.79 | CTSS (0.55) | LMNASMN1; SMN2L3MBTL1CTSKCTSS | |
| SCHEMBL22636139 | 0.79 | CTSS (0.55) | LMNASMN1; SMN2L3MBTL1CTSKCTSS | |
| SCHEMBL15932492 | 0.77 | CTSK (0.51) | LMNASMN1; SMN2L3MBTL1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |