Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23934503 | 0.85 | USP2 (0.45) | USP2TSHRPIN1MTNR1AMTNR1B | |
| SCHEMBL23699401 | 0.78 | DRD2 (0.44) | USP2TSHRMTNR1AMTNR1B | |
| SCHEMBL12924867 | 0.78 | SLC6A3 (0.51) | TSHRALDH1A1KMT2A | |
| SCHEMBL5726924 | 0.77 | PIN1 (0.43) | USP2PIN1 | |
| SCHEMBL23699381 | 0.77 | TSHR (0.44) | USP2TSHRPIN1MTNR1AMTNR1B | |
| SCHEMBL8301035 | 0.77 | PPARG (0.43) | PIN1 | |
| SCHEMBL28750554 | 0.75 | TSHR (0.43) | USP2TSHRPIN1ECE1PDE4A | |
| SCHEMBL8298173 | 0.74 | PPARA (0.53) | — | |
| SCHEMBL31758112 | 0.74 | FFAR1 (0.41) | PIN1ALDH1A1IDO1 | |
| SCHEMBL7961253 | 0.74 | FFAR1 (0.49) | TSHRMTNR1AMTNR1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |