Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298701 | 0.80 | MEN1 (0.54) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL4088432 | 0.79 | MEN1 (0.46) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL3839465 | 0.78 | KMT2A (0.52) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL22624389 | 0.78 | MEN1 (0.42) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL12648858 | 0.78 | MEN1 (0.52) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL6893214 | 0.76 | MEN1 (0.41) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL18242463 | 0.74 | MEN1 (0.43) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL2165280 | 0.72 | MEN1 (0.52) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL30516691 | 0.72 | ALDH1A1 (0.65) | MEN1KMT2ATDP1PTPN2PTPN1 | |
| SCHEMBL13745451 | 0.72 | MEN1 (0.47) | MEN1KMT2ATDP1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968618-A2 | IMAGEABLE EMBOLIC MICROSPHERE | Dreher, Matthew R. (US) | 2016-01-20 | — | — | EP | claimed |
| WO-2014152488-A2 | IMAGEABLE EMBOLIC MICROSPHERE | DREHER MATTHEW R (US) | 2014-09-25 | — | — | WO | claimed |
| CN-115137870-B | Emulsion comprising particles | 生物相容性英国公司 | 2024-05-10 | — | — | CN | disclosed |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | GUERBET (FR) | 2023-09-14 | — | — | US | disclosed |
| US-11672876-B2 | Imageable embolic microsphere | BIOCOMPATIBLES UK LIMITED (GB) | 2023-06-13 | — | — | US | disclosed |
| CN-115137870-A | Emulsions comprising particles | 生物相容性英国公司 | 2022-10-04 | — | — | CN | disclosed |
| CN-114805644-B | Nontransmissive polymer and preparation method and application thereof | 苏州美创医疗科技有限公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114805644-A | Nontransmissive polymer and preparation method and application thereof | 苏州美创医疗科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| US-11383008-B2 | Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2022-07-12 | — | — | US | disclosed |
| CN-108883189-B | Emulsion comprising particles | 生物相容性英国公司 | 2022-06-21 | — | — | CN | disclosed |
| EP-3131897-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-06-15 | — | — | EP | disclosed |
| EP-2968618-A2 | IMAGEABLE EMBOLIC MICROSPHERE | Dreher, Matthew R. (US) | 2016-01-20 | — | — | EP | disclosed |
| US-20150335779-A1 | Method of Embolization using a Radiopaque, Non-Biodegradable, Water-Insoluble Iodinated Benzyl Ether of PolyI(Vinyl Alcohol) | ANTIA THERAPEUTICS S.A. (CH) | 2015-11-26 | — | — | US | disclosed |
| WO-2015160634-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| WO-2015160636-A1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| US-9115230-B2 | Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof | ANTIA THERAPEUTICS S.A. (CH) | 2015-08-25 | — | — | US | disclosed |
| WO-2014152488-A2 | IMAGEABLE EMBOLIC MICROSPHERE | DREHER MATTHEW R (US) | 2014-09-25 | — | — | WO | disclosed |
| US-20130108574-A1 | RADIOPAQUE, NON-BIODEGRADABLE, WATER-INSOLUBLE IODINATED BENZYL ETHERS OF POLY(VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | MERIT MEDICAL SYSTEMS, INC. | 2013-05-02 | — | — | US | disclosed |
| EP-2545085-A1 | RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | Universite Claude Bernard Lyon 1 (UCBL) (FR) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110589-A1 | RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF | UNIVERSITÉ CLAUDE BERNARD LYON 1 (UCBL) (FR) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11672876-B2 | Imageable embolic microsphere | MKI67, PCNA, VHL | MEN1 103/4885KMT2A 2018/4885TDP1 1561/4885 |
| US-11383008-B2 | Surface-modified polymeric substrates grafted with a properties-imparting compound using clip chemistry | CLASP1, MACF1, MICA | MEN1 2423/4885KMT2A 1207/4885TDP1 1917/4885 |
| US-20230285601-A1 | NON DEGRADABLE RADIO-OPAQUE EMBOLISATION MICROSPHERE | KIT, TIE1, HRH4 | MEN1 1587/4885KMT2A 1595/4885TDP1 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.