Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7542304 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHRACHECYP1A2MEN1 | |
| SCHEMBL8613228 | 0.82 | ALDH1A1 (0.43) | ALDH1A1TSHRACHEKDM4ECYP1A2 | |
| SCHEMBL16166884 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TSHRACHEKDM4ECYP1A2 | |
| SCHEMBL16934069 | 0.79 | ACHE (0.46) | ALDH1A1TSHRACHECYP1A2GAA | |
| SCHEMBL23700154 | 0.79 | MYC (0.44) | ALDH1A1TSHRACHEKDM4ECYP1A2 | |
| SCHEMBL7086146 | 0.78 | NFE2L2 (0.39) | ALDH1A1ACHEGAAMGAMSI | |
| SCHEMBL17035490 | 0.78 | ACHE (0.46) | ALDH1A1TSHRACHECYP1A2GAA | |
| SCHEMBL132630 | 0.77 | ALDH1A1 (0.55) | ALDH1A1TSHRKDM4ECYP1A2CYP2C19 | |
| SCHEMBL20992582 | 0.76 | KDM4E (0.43) | ALDH1A1TSHRACHEKDM4ECYP1A2 | |
| SCHEMBL28943441 | 0.76 | CTSL (0.45) | ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030113805-A1 | Intrinsically labelled solid support | ZENECA LIMITED, A LONDON CORPORATION | 2003-06-19 | — | — | US | disclosed |
| US-20010007740-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LTD. | 2001-07-12 | — | — | US | disclosed |
| EP-0843656-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LIMITED (GB) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003931-A1 | INTRINSICALLY LABELLED SOLID SUPPORT | ZENECA LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |