SCHEMBL23701035

SCHEMBL23701035

CCO[SiH](Cl)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.35
LTA4H P09960 1/20 0.34
KCNH2 Q12809 1/20 0.34
TP53 P04637 1/20 0.33
POLB P06746 1/20 0.32
ACHE P22303 1/20 0.32
NR1I2 O75469 1/20 0.32
RELA Q04206 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
GLA P06280 1/20 0.31
ALDH1A1 P00352 2/20 0.30
TSHR P16473 2/20 0.30
AOX1 Q06278 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7023755 0.77 MAPK1 (0.31) POLB
SCHEMBL675683 0.76 LTA4H (0.37) NPSR1LTA4HKCNH2TP53RELA
SCHEMBL704521 0.76 RELA (0.38) NPSR1LTA4HKCNH2TP53POLB
SCHEMBL48956 0.76 LTA4H (0.37) NPSR1LTA4HKCNH2TP53POLB
SCHEMBL8405513 0.73 CA4 (0.38) LTA4HACHEALDH1A1TSHR
SCHEMBL705286 0.73 LTA4H (0.34) NPSR1LTA4HKCNH2TP53RELA
SCHEMBL28112919 0.73 ALDH1A1 (0.34) NPSR1LTA4HKCNH2TP53RELA
SCHEMBL3871670 0.73 LTA4H (0.34) NPSR1LTA4HKCNH2TP53RELA
SCHEMBL29159182 0.73 LTA4H (0.34) NPSR1LTA4HKCNH2TP53RELA
Ethylene SCHEMBL27544639 0.73 LTA4H (0.34) NPSR1LTA4HKCNH2TP53RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed