Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701473 | 0.92 | HRH3 (0.42) | HRH3FFAR4CYP4F2CYP4A11KMT2A | |
| SCHEMBL23709369 | 0.87 | NR1H2 (0.51) | HRH3ABHD6CYP4F2CYP4A11 | |
| SCHEMBL23537968 | 0.86 | ESR1 (0.46) | HRH3ABHD6CYP4F2CYP4A11KMT2A | |
| SCHEMBL23701302 | 0.85 | ADRA2A (0.42) | HRH3FFAR4CYP4F2CYP4A11KMT2A | |
| SCHEMBL29097949 | 0.84 | HRH3 (0.43) | HRH3CYP4F2CYP4A11F10PLG | |
| SCHEMBL23561748 | 0.83 | STS (0.41) | HRH3KMT2A | |
| SCHEMBL29098045 | 0.80 | F10 (0.52) | HRH3HPGDTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL23561871 | 0.79 | NR1H2 (0.53) | HRH3ABHD6CYP4F2CYP4A11 | |
| SCHEMBL30951856 | 0.79 | NR1H2 (0.53) | HRH3ABHD6CYP4F2CYP4A11 | |
| SCHEMBL23561725 | 0.78 | HRH3 (0.55) | HRH3ABHD6KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11992535-B2 | Compounds and probes for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| US-20210236663-A1 | COMPOUNDS AND PROBES FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236663-A1 | COMPOUNDS AND PROBES FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | HRH3 3299/4885FFAR4 4102/4885HPGD 1947/4885 |
| US-11992535-B2 | Compounds and probes for imaging huntingtin protein | HTT, HYPK, HSPBP1 | HRH3 3299/4885FFAR4 4102/4885HPGD 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.