Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16968605 | 0.80 | TRPA1 (0.34) | KCNK3KCNK9CACNA1GCACNA1HCACNA1I | |
| SCHEMBL30139764 | 0.80 | TRPA1 (0.34) | KCNK3KCNK9CACNA1GCACNA1HCACNA1I | |
| SCHEMBL16968545 | 0.74 | RORC (0.34) | — | |
| SCHEMBL24723975 | 0.72 | CHRM2 (0.39) | NPC1ALDH1A1MAPTMAPK1HTT | |
| SCHEMBL21591623 | 0.71 | KMT2A (0.38) | KMT2ALMNAHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL21594157 | 0.71 | KMT2A (0.38) | KMT2ALMNAHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL30496694 | 0.71 | KMT2A (0.38) | KMT2ALMNAHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL21594156 | 0.71 | KMT2A (0.38) | KMT2ALMNAHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL29757593 | 0.71 | KMT2A (0.38) | KMT2ALMNAHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL29757592 | 0.71 | KMT2A (0.38) | KMT2ALMNAHSP90AA1HSP90AB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535614-B2 | Dihydropyrrolopyridine inhibitors of ROR-gamma | VITAE PHARMACEUTICALS, LLC (US) | 2022-12-27 | — | — | US | disclosed |
| US-20210238174-A1 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | VITAE PHARMACEUTICALS, LLC | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238174-A1 | DIHYDROPYRROLOPYRIDINE INHIBITORS OF ROR-GAMMA | RORC, RORB, RORA | KMT2A 3277/4885LMNA 4465/4885HSP90AA1 1940/4885 |
| US-11535614-B2 | Dihydropyrrolopyridine inhibitors of ROR-gamma | RORC, RORB, RORA | KMT2A 3277/4885LMNA 4465/4885HSP90AA1 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.