Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 5/20 | 0.53 |
| ▸ | PRKDC | P78527 | 8/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423315 | 0.73 | TPSAB1 (0.61) | PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL1423130 | 0.70 | HRH3 (0.53) | PNMT | |
| SCHEMBL6424327 | 0.70 | PNMT (1.00) | PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL17385378 | 0.68 | PRKDC (0.45) | PRKDC | |
| SCHEMBL1010536 | 0.68 | IGF1R (0.54) | PNMTHTR2C | |
| SCHEMBL1011359 | 0.68 | ASIC3 (0.59) | PNMTHTR2C | |
| SCHEMBL31083767 | 0.68 | ASIC3 (0.59) | PNMTHTR2C | |
| SCHEMBL21236155 | 0.68 | PNMT (0.63) | PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL12339924 | 0.67 | PNMT (0.49) | PNMTTPSAB1TPSD1TPSG1 | |
| SCHEMBL3441396 | 0.67 | PNMT (0.49) | PNMTTPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014141035-A2 | FUSED HETEROCYCLYL DERIVATIVES AS NAMPT INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-09-18 | — | — | WO | disclosed |
| EP-2545059-A1 | A PROCESS FOR MAKING PRASUGREL | Synthon BV (NL) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110219-A1 | A PROCESS FOR MAKING PRASUGREL | SYNTHON BV (NL) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011110219-A1 | A PROCESS FOR MAKING PRASUGREL | SYNTHON BV (NL) | 2011-09-15 | — | — | WO | disclosed |