Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21710819 | 1.00 | LATS1 (0.30) | LATS1TP53MAPTSMN1; SMN2 | |
| SCHEMBL21678184 | 0.92 | LATS1 (0.31) | LATS1TP53MAPTSMN1; SMN2 | |
| SCHEMBL23701691 | 0.92 | LATS1 (0.31) | LATS1TP53MAPTSMN1; SMN2 | |
| SCHEMBL14607913 | 0.83 | NPC1 (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL13428276 | 0.83 | NPC1 (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL3676503 | 0.83 | NPC1 (0.32) | MAPTSMN1; SMN2 | |
| SCHEMBL21678081 | 0.79 | — | — | |
| SCHEMBL23701699 | 0.79 | — | — | |
| SCHEMBL18269384 | 0.79 | NPC1 (0.33) | MAPTSMN1; SMN2 | |
| SCHEMBL23714371 | 0.73 | APP (0.34) | LATS1TP53MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-11-08 | — | — | US | disclosed |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-10-14 | — | — | US | disclosed |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11492359-B2 | Near-infrared nerve-sparing fluorophores | NTRK1, PMP22, GAP43 | LATS1 2336/4885TP53 869/4885MAPT 636/4885 |
| US-20210236657-A1 | NERVE-SPECIFIC FLUOROPHORE FORMULATIONS FOR DIRECT AND SYSTEMIC ADMINISTRATION | PFAS, NPFFR2, NPFFR1 | LATS1 2009/4885TP53 3690/4885MAPT 1093/4885 |
| US-20210317137-A1 | NEAR-INFRARED NERVE-SPARING FLUOROPHORES | NTRK1, NGF, SMN1; SMN2 | LATS1 3464/4885TP53 532/4885MAPT 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.