Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 8/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701747 | 0.90 | ICMT (0.64) | ICMTTSHRALDH1A1LMNAGLA | |
| SCHEMBL23701758 | 0.89 | ICMT (0.64) | ICMTTSHRALDH1A1LMNAGLA | |
| SCHEMBL9237275 | 0.88 | ICMT (1.00) | ICMTNPSR1 | |
| SCHEMBL30261856 | 0.88 | TSHR (0.66) | ICMTTSHRALDH1A1LMNAGLA | |
| SCHEMBL23701757 | 0.88 | TSHR (0.66) | ICMTTSHRALDH1A1LMNAGLA | |
| SCHEMBL29486509 | 0.85 | ICMT (0.72) | ICMTALDH1A1LMNACYP2C9KDM4E | |
| SCHEMBL24445947 | 0.85 | ICMT (0.72) | ICMTALDH1A1LMNACYP2C9KDM4E | |
| SCHEMBL6116786 | 0.84 | TSHR (0.69) | ICMTTSHRALDH1A1LMNAGLA | |
| SCHEMBL24612560 | 0.84 | TSHR (0.58) | ICMTTSHRALDH1A1LMNAGLA | |
| SCHEMBL29486513 | 0.84 | TSHR (0.58) | ICMTTSHRALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12150447-B2 | Plant growth regulator | UNIVERSITY OF WASHINGTON (US) | 2024-11-26 | — | — | US | disclosed |
| US-20220380782-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | KAKE EDUCATIONAL INSTITUTION (JP) | 2022-12-01 | — | — | US | disclosed |
| EP-4026828-A1 | AUXIN-INDUCIBLE DEGRON SYSTEM KIT AND USE THEREOF | Inter-University Research Institute Corporation Research Organization of Information and Systems (JP) | 2022-07-13 | — | — | EP | disclosed |
| CN-114144400-A | Kit of auxin degradation determining subsystem and application thereof | 大学共同利用机关法人信息系统研究机构 | 2022-03-04 | — | — | CN | disclosed |
| CN-114127294-A | Non-human animals and uses thereof | 大学共同利用机关法人信息系统研究机构 | 2022-03-01 | — | — | CN | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210235697-A1 | PLANT GROWTH REGULATOR | ING2, GHRHR, MYB | ICMT 1658/4885TSHR 57/4885ALDH1A1 3460/4885 |
| US-12150447-B2 | Plant growth regulator | ING2, GHRHR, MYB | ICMT 1658/4885TSHR 57/4885ALDH1A1 3460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.