Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.39 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370540 | 0.92 | TSHR (0.36) | TSHRLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL2370494 | 0.86 | MEN1 (0.39) | LMNAKMT2ACYP3A4CYP2C9CYP2B6 | |
| SCHEMBL2371326 | 0.78 | AKR1C3 (0.38) | TSHRLMNAKMT2AHPGDCYP3A4 | |
| SCHEMBL2371309 | 0.76 | CYP3A4 (0.36) | LMNACYP3A4CYP2C9CYP2B6CYP3A5 | |
| Lithium Ion SCHEMBL2370296 | 0.76 | CYP3A4 (0.36) | LMNACYP3A4CYP2C9CYP2B6CYP3A5 | |
| Potassium Ion SCHEMBL2370572 | 0.76 | CYP3A4 (0.36) | LMNACYP3A4CYP2C9CYP2B6CYP3A5 | |
| SCHEMBL9943519 | 0.73 | CYP2C9 (0.41) | LMNAALDH1A1CYP2C9MAPK1CYP2C19 | |
| SCHEMBL907693 | 0.73 | ALDH1A1 (0.39) | TSHRLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1553635 | 0.71 | CYP3A4 (0.40) | LMNACYP3A4CYP2C9CYP2B6CYP3A5 | |
| SCHEMBL12298619 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545039-A1 | A PROCESS FOR MAKING VORICONAZOLE | Synthon BV (NL) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110198-A1 | A PROCESS FOR MAKING VORICONAZOLE | SYNTHRON B.V. (NL) | 2011-09-15 | — | — | WO | disclosed |