Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161152 | 0.88 | NR4A2 (0.38) | CA1CA2ALDH1A1GAA | |
| Thiobenzoic Acid SCHEMBL2370364 | 0.86 | KMT2A (0.39) | MEN1KMT2AMMP2GSK3BCA1 | |
| Valeric Acid SCHEMBL4154428 | 0.80 | MMP2 (0.42) | KMT2AMMP2GSK3BCA1CA2 | |
| SCHEMBL29086929 | 0.78 | SLC6A3 (0.43) | MEN1KMT2AMMP2GSK3BCA1 | |
| Thiobenzoic Acid SCHEMBL161151 | 0.76 | CA12 (0.48) | CA1CA2ALDH1A1GAA | |
| Thiobenzoic Acid SCHEMBL2354925 | 0.76 | NR4A2 (0.40) | ALDH1A1GAA | |
| Thiobenzoic Acid SCHEMBL28164247 | 0.76 | NR4A2 (0.40) | ALDH1A1GAA | |
| SCHEMBL4229223 | 0.76 | NR4A2 (0.37) | ALDH1A1KDM4EGAA | |
| SCHEMBL17267372 | 0.76 | MEN1 (0.41) | MEN1KMT2AMMP2GSK3BCA1 | |
| SCHEMBL29728055 | 0.75 | GABRP (0.43) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544701-B1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIV UTAH RES FOUND (US) | 2019-08-14 | — | — | EP | disclosed |
| US-9289510-B2 | Polymeric drug delivery conjugates and methods of making and using thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-03-22 | — | — | US | disclosed |
| EP-2544701-A2 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | University of Utah Research Foundation (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112482-A2 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2011-09-15 | — | — | WO | disclosed |