SCHEMBL23704286

SCHEMBL23704286

NCc1cc(I)c(N)cc1F

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377149 0.81 CA1 (0.32)
SCHEMBL4889962 0.79 ALDH1A1 (0.37) LOXL2TAAR1
SCHEMBL29467943 0.79 ALDH1A1 (0.37) LOXL2TAAR1
SCHEMBL1093491 0.76 ALDH1A1 (0.36)
SCHEMBL30788050 0.76 ALDH1A1 (0.36)
SCHEMBL13527770 0.75 LOXL2 (0.42) LOXL2TAAR1
SCHEMBL29467970 0.75 ALDH1A1 (0.37) LOXL2TAAR1
SCHEMBL2004497 0.74 GAA (0.40)
SCHEMBL23707382 0.74 ALDH1A1 (0.50) LOXL2TAAR1
Fluoride SCHEMBL31312733 0.74 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115052860-B Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2024-06-21 CN disclosed
US-20230116201-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-04-13 US disclosed
EP-4097084-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2022-12-07 EP disclosed
CN-115052860-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2022-09-13 CN disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 WO disclosed
WO-2021154902-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230116201-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 LOXL2 539/4885TAAR1 4223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.