Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6423341 | 0.83 | USP2 (0.49) | ESR2NR1H2USP2SMN1; SMN2BRD4 | |
| SCHEMBL17385378 | 0.83 | PRKDC (0.45) | SMN1; SMN2PIK3CAMAPTKDM4EMEN1 | |
| SCHEMBL6421569 | 0.82 | ESR2 (0.55) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL2921637 | 0.79 | ESR2 (0.52) | ESR2NR1H2USP2SMN1; SMN2BRD4 | |
| SCHEMBL12393136 | 0.79 | ESR2 (0.52) | ESR2NR1H2USP2SMN1; SMN2BRD4 | |
| SCHEMBL1017283 | 0.78 | ESR2 (0.54) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL14876121 | 0.78 | NR1H2 (0.60) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL22369230 | 0.78 | ESR2 (0.54) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL32660197 | 0.78 | ESR2 (0.54) | ESR2NR1H2BRD4CREBBPADORA1 | |
| SCHEMBL6198277 | 0.78 | NR1H2 (0.53) | ESR2NR1H2USP2SMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153756-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2022-05-19 | — | — | US | disclosed |
| US-20170121349-A1 | Anti-Infective Compounds | INSTITUT PASTEUR KOREA (KR) | 2017-05-04 | — | — | US | disclosed |
| WO-2015193506-A1 | ANTI-INFECTIVE COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2015-12-23 | — | — | WO | disclosed |
| EP-2545059-A1 | A PROCESS FOR MAKING PRASUGREL | Synthon BV (NL) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110219-A1 | A PROCESS FOR MAKING PRASUGREL | SYNTHON BV (NL) | 2011-09-15 | — | — | WO | disclosed |
| WO-2011110219-A1 | A PROCESS FOR MAKING PRASUGREL | SYNTHON BV (NL) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220153756-A1 | ANTI-INFECTIVE COMPOUNDS | RABGGTB, ELANE, SERPINB1 | ESR2 3165/4885NR1H2 885/4885USP2 3826/4885 |
| US-20170121349-A1 | Anti-Infective Compounds | FNTB, LSS, PGLS | ESR2 3071/4885NR1H2 565/4885USP2 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.