SCHEMBL23706285

SCHEMBL23706285

O=C(O)C(=O)/C=C(\O)c1ccc(F)c(F)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
CYP1A2 P05177 1/20 0.55
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
PTPN1 P18031 1/20 0.45
PLA2G7 Q13093 1/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRNB2 P17787 1/20 0.38
SLC6A2 P23975 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26088990 0.80 CYP1A2 (0.46) CA12CA1CA2CA9CYP1A2
SCHEMBL8040824 0.79 CA1 (0.67) CA12CA1CA2CA9CYP1A2
SCHEMBL8040828 0.79 CA1 (0.67) CA12CA1CA2CA9CYP1A2
SCHEMBL12596961 0.78 ALDH1A1 (0.47) CYP1A2CES2CES1PTPN1PLA2G7
SCHEMBL30051010 0.78 ALDH1A1 (0.47) CYP1A2CES2CES1PTPN1PLA2G7
SCHEMBL1765078 0.77 MAPT (0.46) CYP1A2CES2CES1PTPN1PLA2G7
SCHEMBL7378259 0.75 CA1 (0.67) CA12CA1CA2CA9CYP1A2
SCHEMBL7378257 0.75 CA1 (0.67) CA12CA1CA2CA9CYP1A2
SCHEMBL8046161 0.74 TSHR (0.57) CA12CA1CA2CA9CYP1A2
SCHEMBL8040827 0.74 CA12 (0.55) CA12CA1CA2CA9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024078871-A1 1-PYRIDYL-5-PHENYLPYRAZOLYL-3-OXY- AND -3-THIOALKYL ACIDS AND DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 WO disclosed
EP-4097087-A1 [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS HERBICIDAL INGREDIENTS Bayer Aktiengesellschaft (DE) 2022-12-07 EP disclosed
CN-115003656-A [ (1,4, 5-trisubstituted-1H-pyrazol-3-yl) sulfanyl ] acetic acid derivatives and salts thereof, and their use as active herbicidal agents 拜耳公司 2022-09-02 CN disclosed
WO-2021151976-A1 [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS HERBICIDAL INGREDIENTS BAYER AKTIENGESELLSCHAFT (DE) 2021-08-05 WO disclosed