Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236969 | 0.81 | NPFFR1 (0.40) | ALDH1A1GAARAB9AMAPTMEN1 | |
| SCHEMBL23709478 | 0.80 | NPC1 (0.49) | ALDH1A1GAAKDM4ELMNARAB9A | |
| SCHEMBL22925025 | 0.78 | LMNA (0.60) | ALDH1A1KDM4ELMNARAB9AMAPT | |
| SCHEMBL2447369 | 0.77 | NPFFR1 (0.43) | ALDH1A1KDM4ERAB9AMAPTMEN1 | |
| SCHEMBL2447368 | 0.77 | NPFFR1 (0.43) | ALDH1A1KDM4ERAB9AMAPTMEN1 | |
| SCHEMBL22925138 | 0.77 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4ELMNARAB9A | |
| SCHEMBL16993676 | 0.77 | LMNA (0.44) | ALDH1A1KDM4ELMNARAB9AKMT2A | |
| SCHEMBL16993675 | 0.77 | LMNA (0.44) | ALDH1A1KDM4ELMNARAB9AKMT2A | |
| SCHEMBL22925065 | 0.77 | NPFFR1 (0.37) | NPFFR1NPFFR2APPKIF11AR | |
| Hydrochloric Acid SCHEMBL6510408 | 0.76 | LMNA (0.43) | ALDH1A1KDM4ELMNARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |