Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.39 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23710189 | 0.91 | CTSL (0.41) | KISS1ROPRM1CXCR4CTSLCTSH | |
| SCHEMBL23710225 | 0.91 | CTSL (0.41) | KISS1ROPRM1CXCR4CTSLCTSH | |
| SCHEMBL23710234 | 0.89 | KISS1R (0.52) | KISS1ROPRM1OPRD1OPRK1TACR1 | |
| SCHEMBL23700288 | 0.82 | KISS1R (0.53) | KISS1ROPRM1TACR1CXCR4NTSR2 | |
| SCHEMBL23700286 | 0.82 | KISS1R (0.53) | KISS1ROPRM1TACR1CXCR4NTSR2 | |
| SCHEMBL23700290 | 0.82 | KISS1R (0.53) | KISS1ROPRM1TACR1CXCR4NTSR2 | |
| SCHEMBL23710188 | 0.81 | OPRM1 (0.51) | KISS1ROPRM1TACR1CXCR4CTSL | |
| SCHEMBL23710223 | 0.80 | OPRM1 (0.50) | KISS1ROPRM1TACR1CXCR4CTSL | |
| SCHEMBL23710323 | 0.80 | CAPN1 (0.49) | KISS1ROPRM1TACR1CXCR4TACR2 | |
| SCHEMBL23710322 | 0.80 | KISS1R (0.45) | KISS1ROPRM1TACR1CXCR4TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238225-A1 | PEPTIDOMIMETIC INHIBITORS OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PIN1) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238225-A1 | PEPTIDOMIMETIC INHIBITORS OF THE PEPTIDYL-PROLYL CIS/TRANS ISOMERASE (PIN1) | PIN1, PPIA, PPIE | KISS1R 4542/4885OPRM1 3964/4885OPRD1 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.