Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | PPM1B | O75688 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18202479 | 1.00 | MEN1 (0.42) | MEN1KMT2AMAPTHSD17B10BCHE | |
| SCHEMBL24772411 | 1.00 | MEN1 (0.42) | MEN1KMT2AMAPTHSD17B10BCHE | |
| SCHEMBL9618911 | 0.84 | BCHE (0.48) | MEN1KMT2AMAPTHSD17B10BCHE | |
| SCHEMBL9921160 | 0.84 | BCHE (0.48) | MEN1KMT2AMAPTHSD17B10BCHE | |
| SCHEMBL18288604 | 0.83 | TRPM8 (0.45) | MEN1KMT2AMAPTHSD17B10BCHE | |
| SCHEMBL1751897 | 0.76 | LMNA (0.48) | MEN1KMT2AMAPTHSD17B10CHRNA7 | |
| SCHEMBL637664 | 0.76 | LMNA (0.48) | MEN1KMT2AMAPTHSD17B10CHRNA7 | |
| SCHEMBL636837 | 0.76 | LMNA (0.48) | MEN1KMT2AMAPTHSD17B10CHRNA7 | |
| SCHEMBL20067804 | 0.74 | BCHE (0.40) | MEN1KMT2AMAPTHSD17B10BCHE | |
| SCHEMBL16140946 | 0.74 | BCHE (0.50) | MEN1KMT2ABCHECHRNA7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238595-A1 | MODIFIED RNA AGENTS WITH REDUCED OFF-TARGET EFFECT | ALNYLAM PHARMACEUTICALS, INC. (US) | 2021-08-05 | — | — | US | disclosed |