Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22313470 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SLC18A3SPHK1NOS3NOS1 | |
| SCHEMBL8121053 | 0.77 | SLC18A3 (0.60) | ALDH1A1SLC18A3PSMB5KDM4E | |
| SCHEMBL5146741 | 0.76 | RAB9A (0.50) | ALDH1A1SLC18A3NOS3NOS1NOS2 | |
| SCHEMBL10052123 | 0.75 | SLC18A3 (0.58) | ALDH1A1SLC18A3PSMB5KDM4E | |
| SCHEMBL20210323 | 0.75 | SLC18A3 (0.46) | ALDH1A1SLC18A3NOS3NOS1NOS2 | |
| SCHEMBL9023189 | 0.74 | SPHK1 (0.43) | SLC18A3SPHK1 | |
| SCHEMBL23691297 | 0.74 | HTT (0.43) | ALDH1A1SLC18A3NOS3NOS1NOS2 | |
| SCHEMBL5144890 | 0.74 | RAB9A (0.49) | ALDH1A1SLC18A3NOS3NOS1NOS2 | |
| SCHEMBL26154043 | 0.72 | SLC18A3 (0.56) | ALDH1A1SLC18A3PSMB5KDM4E | |
| SCHEMBL762444 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155317-A1 | ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF EXTRACELLULAR PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2021-08-05 | — | — | WO | disclosed |