Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.35 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6026760 | 0.80 | NPC1 (0.44) | TAAR1ALDH1A1 | |
| SCHEMBL2093023 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ACHEALOX5 | |
| SCHEMBL12679031 | 0.72 | HRH3 (1.00) | HRH3TAAR1ALDH1A1TSHRBRD4 | |
| SCHEMBL20582831 | 0.72 | CYP19A1 (0.41) | TAAR1ALDH1A1 | |
| SCHEMBL5544382 | 0.72 | PDPK1 (0.41) | TAAR1ALDH1A1 | |
| SCHEMBL5539570 | 0.72 | RAB9A (0.41) | ALDH1A1 | |
| SCHEMBL695101 | 0.71 | KDM4E (0.46) | ALDH1A1ALOX5 | |
| SCHEMBL315880 | 0.71 | PDPK1 (0.43) | ALDH1A1 | |
| SCHEMBL6603416 | 0.70 | — | — | |
| SCHEMBL659509 | 0.69 | HRH3 (0.82) | HRH3TAAR1ALDH1A1TSHRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084811-B2 | Compounds for treatment of cancer | Oncternal Therapeutics, Inc. (US) | 2021-08-10 | — | — | US | disclosed |
| CN-103442566-B | The compound of Therapeutic cancer | GTX, INC. (US) | 2015-12-09 | — | — | CN | disclosed |
| CN-102883607-B | Compounds for the treatment of cancer | GTX INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104592205-A | COMPOUNDS FOR TREATMENT OF CANCER | GTX INC | 2015-05-06 | — | — | CN | disclosed |
| CN-103442566-A | Compounds for treatment of cancer | GTX INC | 2013-12-11 | — | — | CN | disclosed |
| CN-102883607-A | Compounds for the treatment of cancer | GTX INC (US) | 2013-01-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084811-B2 | Compounds for treatment of cancer | KLK3, BRDT, ACP3 | HRH3 3503/4885TAAR1 4514/4885ALDH1A1 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.