Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23504954 | 0.77 | THRB (0.34) | — | |
| SCHEMBL31473489 | 0.75 | — | — | |
| SCHEMBL13503506 | 0.72 | — | — | |
| SCHEMBL104342 | 0.72 | — | — | |
| SCHEMBL19705361 | 0.70 | ALDH1A1 (0.47) | GAAL3MBTL1 | |
| SCHEMBL23319723 | 0.70 | GAA (0.46) | DRD2DRD3GAAL3MBTL1MDM2 | |
| SCHEMBL19966112 | 0.70 | ALDH1A1 (0.47) | GAAL3MBTL1 | |
| SCHEMBL22369902 | 0.70 | ALDH1A1 (0.47) | GAAL3MBTL1 | |
| SCHEMBL278463 | 0.70 | ALDH1A1 (0.47) | GAAL3MBTL1 | |
| SCHEMBL18844888 | 0.70 | ALDH1A1 (0.47) | GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668871-B1 | 6-AMINO-7,9-DIHYDRO-8H-PURIN-8-ONE DERIVATIVES AS IMMUNOSTIMULANT TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2021-08-04 | — | — | EP | disclosed |