⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704874 | 0.84 | NR3C1 (0.31) | — | |
| SCHEMBL23704891 | 0.82 | PGR (0.31) | — | |
| SCHEMBL23714886 | 0.78 | RXRA (0.33) | — | |
| SCHEMBL23714875 | 0.77 | CHRNA1 (0.31) | — | |
| SCHEMBL23704923 | 0.76 | BACE1 (0.36) | — | |
| SCHEMBL23714683 | 0.73 | — | — | |
| SCHEMBL23705792 | 0.72 | — | — | |
| SCHEMBL23715054 | 0.72 | — | — | |
| SCHEMBL23714665 | 0.68 | OPRM1 (0.30) | — | |
| SCHEMBL30041832 | 0.66 | RARB (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |