Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23714664 | 0.81 | HTR5A (0.30) | — | |
| SCHEMBL23714629 | 0.75 | PDK2 (0.36) | PDK2 | |
| SCHEMBL23714665 | 0.71 | OPRM1 (0.30) | — | |
| SCHEMBL23714632 | 0.71 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL16264303 | 0.69 | ALDH1A1 (0.34) | — | |
| SCHEMBL23705015 | 0.69 | BACE1 (0.35) | PDK2 | |
| SCHEMBL23715100 | 0.67 | ACHE (0.32) | — | |
| SCHEMBL16172610 | 0.66 | SLC5A1 (0.34) | — | |
| SCHEMBL25865326 | 0.66 | AVPR1A (0.35) | — | |
| SCHEMBL23715103 | 0.66 | ACHE (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |