Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CHRND | Q07001 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23704878 | 0.87 | CHRNA1 (0.40) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL23705409 | 0.73 | HCAR3 (0.43) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL9918032 | 0.67 | OPRD1 (0.44) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL23715111 | 0.67 | CHRNA1 (0.45) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL8122310 | 0.66 | MEN1 (0.38) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL28239960 | 0.65 | ALDH1A1 (0.44) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL22306040 | 0.65 | BACE1 (0.47) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL26394913 | 0.65 | CHRNA1 (0.42) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL16383426 | 0.65 | CHRNA1 (0.37) | HCAR3HCAR2ALDH1A1CHRNA1CHRNG | |
| SCHEMBL14940053 | 0.65 | S100A4 (0.43) | HCAR3HCAR2ALDH1A1UTS2RBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |