Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NAT1 | P18440 | 1/20 | 0.40 |
| ▸ | UNG | P13051 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.34 |
| ▸ | C1S | P09871 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10060473 | 0.82 | CA2 (0.48) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL41941 | 0.79 | CA12 (0.47) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL30402657 | 0.79 | CA12 (0.47) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL6853269 | 0.78 | ALDH1A1 (0.50) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL31604493 | 0.78 | ALDH1A1 (0.50) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL14674759 | 0.77 | ALDH1A1 (0.44) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL16712226 | 0.76 | CA1 (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL5319929 | 0.76 | TYR (0.50) | ALDH1A1CYP2A6TYRGRIA4 | |
| SCHEMBL11735462 | 0.76 | PSIP1 (0.52) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL11965108 | 0.75 | LOXL2 (0.42) | CA1CA2ALDH1A1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |