Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200473 | 0.80 | ALDH1A1 (0.39) | HSD17B10SMN1; SMN2HPGDALDH1A1GAA | |
| SCHEMBL11993823 | 0.78 | IDO1 (0.47) | MEN1KMT2ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL14216506 | 0.77 | L3MBTL1 (0.40) | KMT2AHSD17B10SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL24638630 | 0.76 | BCHE (0.30) | ACHE | |
| SCHEMBL8154014 | 0.76 | MEN1 (0.46) | MEN1KMT2AHSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL1170022 | 0.75 | CYP46A1 (0.56) | MEN1KMT2ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL30364839 | 0.75 | CYP46A1 (0.56) | MEN1KMT2ASMN1; SMN2HPGDTDP1 | |
| SCHEMBL20133593 | 0.75 | MEN1 (0.42) | MEN1KMT2AHSD17B10SMN1; SMN2TDP1 | |
| SCHEMBL22175942 | 0.74 | KCNMA1 (0.44) | MEN1KMT2AHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL11865534 | 0.74 | MEN1 (0.44) | MEN1KMT2AHSD17B10SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155316-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |