Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663941 | 0.88 | MEN1 (0.39) | S1PR1S1PR3MEN1KMT2ALMNA | |
| SCHEMBL23715848 | 0.87 | RAB9A (0.38) | TP53SMN1; SMN2S1PR1S1PR3MEN1 | |
| SCHEMBL10272604 | 0.81 | CRHR1 (0.38) | APLNRS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17664085 | 0.81 | PARP1 (0.37) | SMN1; SMN2S1PR1S1PR3LMNAPARP1 | |
| SCHEMBL21903269 | 0.73 | SLC6A4 (0.38) | KLKB1 | |
| SCHEMBL24295517 | 0.72 | P2RX3 (0.37) | L3MBTL1S1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17664014 | 0.72 | PARP1 (0.38) | SMN1; SMN2MEN1KMT2ALMNAPARP1 | |
| SCHEMBL10235257 | 0.71 | S1PR1 (0.32) | TDP1L3MBTL1SMN1; SMN2S1PR1S1PR3 | |
| SCHEMBL17664049 | 0.71 | PARP1 (0.35) | S1PR1S1PR3PARP1 | |
| SCHEMBL17663880 | 0.70 | HSP90AB1 (0.40) | SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |