Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583934 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL16838610 | 0.81 | MAPT (0.50) | ALDH1A1KMT2ARAB9ANPC1CYP1A2 | |
| SCHEMBL2537569 | 0.80 | CYP3A4 (0.54) | ALDH1A1KMT2ACYP3A4CYP2C9MAPK1 | |
| SCHEMBL23715809 | 0.80 | NPC1 (0.50) | ALDH1A1KMT2ARAB9ANPC1CYP3A4 | |
| SCHEMBL11260997 | 0.80 | CYP3A4 (0.48) | ALDH1A1KMT2ACYP3A4CYP2C9MAPK1 | |
| SCHEMBL28568153 | 0.76 | SYK (0.52) | ALDH1A1KMT2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28085739 | 0.75 | MAPT (0.52) | KMT2ARAB9ANPC1CYP1A2CYP3A4 | |
| SCHEMBL2482554 | 0.75 | RAB9A (0.50) | KMT2ARAB9ANPC1MAPK1MEN1 | |
| SCHEMBL7576573 | 0.75 | RAB9A (0.49) | ALDH1A1KMT2ARAB9ANPC1MAPK1 | |
| SCHEMBL13240816 | 0.75 | RAB9A (0.50) | KMT2ARAB9ANPC1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |