Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7583544 | 0.88 | LMNA (0.51) | RAB9ANPC1POLBFPR2ALDH1A1 | |
| SCHEMBL7583934 | 0.86 | ALDH1A1 (0.49) | RAB9ANPC1POLBFPR2ALDH1A1 | |
| SCHEMBL2482554 | 0.82 | RAB9A (0.50) | RAB9ANPC1FPR2KDM4EGAA | |
| SCHEMBL13240816 | 0.82 | RAB9A (0.50) | RAB9ANPC1FPR2KDM4EGAA | |
| Hydrochloric Acid SCHEMBL2485885 | 0.81 | RAB9A (0.49) | RAB9ANPC1FPR2KDM4EGAA | |
| SCHEMBL28085797 | 0.79 | FPR2 (0.44) | NPC1FPR2ALDH1A1KDM4EGAA | |
| SCHEMBL2715461 | 0.79 | FPR2 (0.44) | NPC1FPR2ALDH1A1KDM4EGAA | |
| SCHEMBL23148267 | 0.78 | FPR2 (0.43) | RAB9ANPC1POLBFPR2ALDH1A1 | |
| SCHEMBL7576014 | 0.78 | SMN1; SMN2 (0.60) | RAB9ANPC1ALDH1A1GAAMAPT | |
| SCHEMBL23148268 | 0.78 | FPR2 (0.43) | RAB9ANPC1POLBFPR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |