Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716306 | 0.74 | S1PR3 (0.56) | ARS1PR3 | |
| SCHEMBL23715950 | 0.71 | AR (0.45) | ARMRGPRX4S1PR3ESRRA | |
| SCHEMBL25680960 | 0.66 | AR (0.44) | ARMRGPRX4ESRRA | |
| SCHEMBL23716119 | 0.65 | S1PR3 (0.44) | ARS1PR3 | |
| SCHEMBL509379 | 0.64 | AR (0.50) | ARMRGPRX4 | |
| SCHEMBL24074650 | 0.63 | AR (0.46) | ARMRGPRX4 | |
| SCHEMBL13762841 | 0.62 | AR (0.49) | ARMRGPRX4S1PR3 | |
| SCHEMBL28338571 | 0.62 | AR (0.45) | ARMRGPRX4S1PR3ESRRA | |
| SCHEMBL6110658 | 0.61 | AR (0.43) | ARMRGPRX4ESRRA | |
| SCHEMBL16255446 | 0.60 | MRGPRX4 (0.51) | ARMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |