Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 19/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716085 | 0.93 | S1PR3 (0.65) | S1PR3S1PR1S1PR4S1PR2AR | |
| SCHEMBL23716119 | 0.81 | S1PR3 (0.44) | S1PR3S1PR1S1PR4S1PR2AR | |
| SCHEMBL23716081 | 0.76 | S1PR3 (0.41) | S1PR3S1PR1S1PR4S1PR2AR | |
| SCHEMBL23716245 | 0.74 | AR (0.40) | S1PR3AR | |
| SCHEMBL23716140 | 0.74 | S1PR3 (0.32) | S1PR3 | |
| SCHEMBL23716127 | 0.73 | OGG1 (0.35) | S1PR3S1PR2 | |
| SCHEMBL23716130 | 0.72 | S1PR3 (0.45) | S1PR3S1PR1S1PR4S1PR2AR | |
| SCHEMBL17664046 | 0.72 | S1PR3 (1.00) | S1PR3S1PR1S1PR4S1PR2 | |
| SCHEMBL19196473 | 0.72 | S1PR3 (1.00) | S1PR3S1PR1S1PR4S1PR2 | |
| SCHEMBL23716062 | 0.67 | SIGMAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |