Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17664012 | 0.85 | SMN1; SMN2 (0.50) | ALDH1A1LMNASMN1; SMN2POLBPDE3B | |
| SCHEMBL23716436 | 0.80 | TRPM8 (0.41) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27433056 | 0.79 | MEN1 (0.66) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL17173719 | 0.70 | CCR1 (0.34) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL15325999 | 0.69 | SLC5A2 (0.51) | ALDH1A1LMNASMN1; SMN2LTA4H | |
| SCHEMBL4292188 | 0.69 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2ALOX5NPSR1 | |
| SCHEMBL27746661 | 0.69 | LTA4H (0.46) | ALDH1A1LMNASMN1; SMN2DCTPP1MEN1 | |
| Ammonia Solution, Strong SCHEMBL29153964 | 0.69 | PDE3B (0.58) | ALDH1A1LMNASMN1; SMN2POLBPDE3B | |
| SCHEMBL1445884 | 0.69 | PDE10A (0.73) | ALDH1A1LMNASMN1; SMN2PDE3BPDE3A | |
| SCHEMBL17851265 | 0.68 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |