Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL23716277 | 0.85 | ALDH1A1 (0.48) | SMN1; SMN2LMNAALDH1A1POLBMAPT | |
| SCHEMBL17663880 | 0.83 | HSP90AB1 (0.40) | SMN1; SMN2LMNAALDH1A1TSHRCYP2C9 | |
| SCHEMBL27433056 | 0.81 | MEN1 (0.66) | SMN1; SMN2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL17664019 | 0.74 | ALDH1A1 (0.53) | SMN1; SMN2LMNAALDH1A1TSHRPOLB | |
| SCHEMBL17664014 | 0.74 | PARP1 (0.38) | SMN1; SMN2LMNAALDH1A1TSHRCYP2C9 | |
| SCHEMBL20448014 | 0.73 | MAOB (0.50) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13500477 | 0.72 | LMNA (0.51) | SMN1; SMN2LMNAALDH1A1TSHRCYP2C9 | |
| SCHEMBL14880495 | 0.72 | LTA4H (0.65) | SMN1; SMN2LMNAALDH1A1TSHRMAPT | |
| Ammonia Solution, Strong SCHEMBL29153964 | 0.71 | PDE3B (0.58) | SMN1; SMN2LMNAALDH1A1POLBPDE3B | |
| SCHEMBL22912582 | 0.71 | L3MBTL1 (0.41) | SMN1; SMN2LMNAALDH1A1TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |
| WO-2016053855-A1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-07 | — | — | WO | disclosed |