Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716062 | 0.80 | SIGMAR1 (0.31) | — | |
| SCHEMBL23716306 | 0.74 | S1PR3 (0.56) | S1PR3 | |
| SCHEMBL23716127 | 0.72 | OGG1 (0.35) | S1PR3 | |
| SCHEMBL23716085 | 0.65 | S1PR3 (0.65) | S1PR3 | |
| SCHEMBL23716119 | 0.65 | S1PR3 (0.44) | S1PR3 | |
| SCHEMBL23716330 | 0.64 | MDM2 (0.38) | S1PR3LMNA | |
| SCHEMBL5446367 | 0.61 | GAA (0.40) | LMNAMAPK1NLRP1PRSS1PRSS2 | |
| SCHEMBL23716437 | 0.58 | S1PR3 (0.37) | S1PR3LMNA | |
| SCHEMBL2602714 | 0.57 | LMNA (0.46) | LMNAMAPK1NLRP1 | |
| SCHEMBL23716193 | 0.57 | OGG1 (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |