Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 7/20 | 0.39 |
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19989690 | 0.87 | GRM5 (0.52) | NAMPTGRM5 | |
| SCHEMBL12489069 | 0.79 | ALDH1A1 (0.44) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL19989626 | 0.78 | DRD2 (0.44) | DRD2DRD4DRD3 | |
| SCHEMBL22324962 | 0.77 | QDPR (0.47) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL25167305 | 0.75 | ALDH1A1 (0.47) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL19989614 | 0.74 | DRD2 (0.41) | DRD2DRD4DRD3 | |
| SCHEMBL23306373 | 0.74 | ALDH1A1 (0.48) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| Trifluoroacetic Acid SCHEMBL19989616 | 0.73 | WNT3A (0.38) | QDPR | |
| SCHEMBL29412345 | 0.73 | NAMPT (0.45) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1577622 | 0.73 | ALDH1A1 (0.45) | NAMPTQDPRALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3519387-B1 | TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | DONG A ST CO LTD (KR) | 2021-08-11 | — | — | EP | disclosed |