⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23846720 | 0.87 | RORC (0.30) | — | |
| SCHEMBL20780321 | 0.79 | CCR4 (0.34) | — | |
| SCHEMBL18855158 | 0.74 | LMNA (0.32) | — | |
| SCHEMBL25998129 | 0.73 | SLC6A3 (0.34) | — | |
| SCHEMBL12877376 | 0.73 | NOS1 (0.41) | — | |
| SCHEMBL23846745 | 0.71 | HPGD (0.30) | — | |
| SCHEMBL22757495 | 0.69 | — | — | |
| SCHEMBL21963064 | 0.69 | — | — | |
| SCHEMBL22222428 | 0.68 | HRH1 (0.34) | — | |
| SCHEMBL25053708 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236442-A1 | METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2021-08-05 | — | — | US | disclosed |