Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.52 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.52 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.50 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320080 | 0.83 | RAB9A (0.48) | TSHRSMN1; SMN2KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL22828238 | 0.83 | RAB9A (0.46) | TSHREPHX1KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL23320044 | 0.74 | RAB9A (0.46) | TP53SMN1; SMN2RAB9AIDO1NPC1 | |
| Diphenylurea SCHEMBL133103 | 0.73 | SMN1; SMN2 (1.00) | TSHRTP53EPHX1EPHX2CDK9 | |
| SCHEMBL5378514 | 0.73 | RAB9A (0.40) | TSHRRAB9AMAOAMAOB | |
| SCHEMBL19732074 | 0.72 | TSHR (0.59) | TSHRTP53EPHX1EPHX2CDK9 | |
| Diphenylurea SCHEMBL3037927 | 0.71 | SMN1; SMN2 (0.94) | TSHRTP53EPHX1EPHX2CDK9 | |
| Diphenylurea SCHEMBL29392345 | 0.71 | SMN1; SMN2 (0.94) | TSHRTP53EPHX1EPHX2CDK9 | |
| Diphenylurea SCHEMBL28431956 | 0.71 | SMN1; SMN2 (0.94) | TSHRTP53EPHX1EPHX2CDK9 | |
| Diphenylurea SCHEMBL30786615 | 0.71 | SMN1; SMN2 (0.94) | TSHRTP53EPHX1EPHX2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230106899-A1 | METHODS OF TREATING CANCER | NOVARTIS PHARMA AG (CH) | 2023-04-06 | — | — | US | disclosed |
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | TSHR 4487/4885TP53 10/4885EPHX1 941/4885 |
| US-20230106899-A1 | METHODS OF TREATING CANCER | STING1, CGAS, TBK1 | TSHR 2046/4885TP53 15/4885EPHX1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.