Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23320080 | 0.78 | RAB9A (0.48) | RAB9AHSP90AA1HSP90AB1TSHRNOS1 | |
| SCHEMBL19367721 | 0.74 | CYP2C9 (0.55) | TSHRCYP2C9CYP3A4 | |
| SCHEMBL5369097 | 0.74 | TSHR (0.42) | RAB9AHSP90AA1HSP90AB1FGFR1TSHR | |
| SCHEMBL3272205 | 0.74 | CYP3A4 (0.53) | RAB9AHSP90AA1HSP90AB1FGFR1NOS1 | |
| SCHEMBL23719141 | 0.73 | TSHR (0.53) | RAB9ATSHRMAOAMAOB | |
| SCHEMBL23320044 | 0.72 | RAB9A (0.46) | RAB9AHSP90AA1HSP90AB1HTT | |
| SCHEMBL17532964 | 0.71 | SLC22A12 (0.38) | RAB9AHSP90AA1HSP90AB1NOS1CYP2C9 | |
| SCHEMBL10183098 | 0.71 | HSP90AA1 (0.41) | RAB9AHSP90AA1HSP90AB1FGFR1NOS1 | |
| SCHEMBL20033972 | 0.71 | HSP90AA1 (0.51) | RAB9AHSP90AA1HSP90AB1FGFR1NOS1 | |
| SCHEMBL544333 | 0.69 | NOS1 (0.42) | RAB9AHSP90AA1HSP90AB1FGFR1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238212-B2 | Imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2007-07-03 | — | — | US | claimed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | claimed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | claimed |
| US-7238212-B2 | Imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | L'OREAL, S.A. (FR) | 2005-01-20 | — | — | US | disclosed |
| EP-1484049-A1 | Imidazole compounds and their use for dyeing of keratinous fibres | L'OREAL (FR) | 2004-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050011019-A1 | Novel imidazole compounds and use of these compounds for dyeing keratinous fibers | KRT18, VIM, NDUFS6 | RAB9A 3755/4885HSP90AA1 3009/4885HSP90AB1 2588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.