Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | PIM1 | P11309 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.47 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828679 | 0.84 | KMT2A (0.54) | NPC1RAB9ACPB1KMT2AMEN1 | |
| SCHEMBL23719173 | 0.83 | CPB1 (0.43) | NPC1RAB9ASMN1; SMN2EPHX1OTUD7B | |
| SCHEMBL27567730 | 0.81 | HSD17B10 (0.53) | NPC1RAB9ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL6213955 | 0.77 | OTUD7B (0.46) | SMN1; SMN2TP53OTUD7BCPB1KMT2A | |
| SCHEMBL27507812 | 0.74 | SMN1; SMN2 (0.59) | NPC1RAB9ASMN1; SMN2ADORA3TSHR | |
| SCHEMBL22246719 | 0.72 | NR2E1 (0.55) | NPC1RAB9AADORA3OTUD7BUSP30 | |
| Diphenylurea SCHEMBL133103 | 0.72 | SMN1; SMN2 (1.00) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL19375825 | 0.72 | ACVR1 (0.41) | NPC1RAB9AOTUD7BCPB1USP30 | |
| SCHEMBL23719194 | 0.71 | MAPT (0.68) | NPC1RAB9ASMN1; SMN2ADORA3PIM1 | |
| SCHEMBL9317689 | 0.70 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2ADORA3PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | NOVARTIS PHARMA AG (CH) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210236466-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | STING1, CGAS, IRF3 | NPC1 859/4885RAB9A 876/4885SMN1; SMN2 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.