Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 14/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 2/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13207148 | 0.84 | ALDH1A1 (0.45) | ALDH1A1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL5175887 | 0.82 | ALDH1A1 (0.68) | ALDH1A1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL31482179 | 0.81 | ADRA1A (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4334091 | 0.81 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL2862492 | 0.81 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| Hydrochloric Acid SCHEMBL18145297 | 0.79 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3155682 | 0.79 | L3MBTL3 (0.59) | ALDH1A1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL920485 | 0.79 | L3MBTL3 (0.59) | ALDH1A1L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL6627476 | 0.78 | HRH3 (0.42) | ALDH1A1MEN1KMT2AHRH3 | |
| SCHEMBL8490717 | 0.78 | CHRM1 (0.56) | ALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |