Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL3 | Q96JM7 | 11/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10859973 | 0.85 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL18185576 | 0.82 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL12881569 | 0.82 | ALDH1A1 (0.97) | ALDH1A1SMN1; SMN2L3MBTL3L3MBTL1MEN1 | |
| SCHEMBL2371949 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3592530 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3592527 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL31482179 | 0.81 | ADRA1A (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL2862492 | 0.81 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL4334091 | 0.81 | L3MBTL3 (0.58) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL31334651 | 0.79 | CHRM1 (0.45) | ALDH1A1L3MBTL3L3MBTL1MBTD1TP53BP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1868605-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006105304-A2 | PHENYL AND PYRIDYL LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | WO | disclosed |
| EP-1478437-A1 | ACC INHIBITORS | Pfizer Products Inc. (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072197-A1 | ACC INHIBITORS | PFIZER PRODUCTS INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| EP-1339691-A1 | NOVEL COMPOUNDS | GlaxoSmithKline S.p.A. (IT) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002044154-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE SPA (IT) | 2002-06-06 | — | — | WO | disclosed |