Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720153 | 0.84 | TDP1 (0.36) | TDP1PSIP1GRM2MMP2MMP3 | |
| SCHEMBL23720151 | 0.84 | TDP1 (0.36) | TDP1PSIP1GRM2MMP2MMP3 | |
| SCHEMBL23720027 | 0.84 | TDP1 (0.36) | TDP1PSIP1GRM2MMP2MMP3 | |
| SCHEMBL23720028 | 0.77 | GAA (0.42) | TDP1PSIP1ALDH1A1TSHRHTR7 | |
| SCHEMBL23720030 | 0.77 | GAA (0.42) | TDP1PSIP1ALDH1A1TSHRHTR7 | |
| SCHEMBL23720198 | 0.74 | GAA (0.37) | ALDH1A1HTR7GAA | |
| SCHEMBL23720115 | 0.70 | GAA (0.37) | TDP1PSIP1ALDH1A1TSHRHTR7 | |
| SCHEMBL23720197 | 0.70 | GAA (0.37) | TDP1PSIP1ALDH1A1TSHRHTR7 | |
| SCHEMBL23720158 | 0.70 | GAA (0.37) | TDP1PSIP1ALDH1A1TSHRHTR7 | |
| SCHEMBL9430740 | 0.64 | GRM2 (0.42) | TDP1PSIP1GRM2MMP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | ADH1A, ADH1C, ADH5 | TDP1 2082/4885PSIP1 2296/4885GRM2 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.