SCHEMBL9430740

SCHEMBL9430740

CCCCCC1ON1S(=O)(=O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 6/20 0.42
TDP1 Q9NUW8 1/20 0.41
GAA P10253 1/20 0.40
PKM P14618 1/20 0.40
POLB P06746 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PSIP1 O75475 1/20 0.38
MMP2 P08253 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
ABCB1 P08183 1/20 0.36
ACHE P22303 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18660656 0.75 ACHE (0.45) GRM2TDP1GAAPKML3MBTL1
SCHEMBL19020647 0.71 L3MBTL1 (0.53) GAAPOLBL3MBTL1PSIP1MMP2
SCHEMBL11459599 0.67 PARL (0.44) GRM2PKML3MBTL1MMP2
SCHEMBL10723979 0.66 PKM (0.70) TDP1GAAPKMPOLBL3MBTL1
SCHEMBL10724287 0.66 POLB (0.59) GAAPKMPOLB
SCHEMBL7130436 0.66 POLB (0.59) GAAPKMPOLB
SCHEMBL10721938 0.66 POLB (0.59) GAAPKMPOLB
Benzenesulfonamide SCHEMBL27948964 0.65 CA2 (0.70) TDP1PSIP1
Hexane SCHEMBL27501792 0.65 TSHR (0.70) TDP1POLBPSIP1CYP2D6
SCHEMBL8567044 0.65 L3MBTL1 (0.42) PKMPOLBL3MBTL1MMP2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023114615-A1 OXIDATIVE CYCLIZATION REAGENTS FOR CHEMOSELECTIVE TRYPTOPHAN BIOCONJUGATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-22 WO disclosed
US-10000651-B2 Metal nanoparticle composite body, metal colloidal solution, and methods for producing these DIC CORPORATION (JP) 2018-06-19 US disclosed
CN-104321153-B Metal nanoparticle complex, colloidal metal solution and their manufacture method DIC株式会社 2016-06-15 CN disclosed
US-20150203700-A1 METAL NANOPARTICLE COMPOSITE BODY, METAL COLLOIDAL SOLUTION, AND METHODS FOR PRODUCING THESE DIC CORPORATION (JP) 2015-07-23 US disclosed
CN-104321153-A Metal nanoparticle composite body, metal colloidal solution, and method for producing metal colloidal solution DAINIPPON INK & CHEMICALS 2015-01-28 CN disclosed
US-5354871-A Pyrroline N-oxide derivatives NATIONAL RESEARCH COUNCIL OF CANADA (CA) 1994-10-11 US disclosed
US-5001233-A Synthesis of hydroxylamines using dioxiranes THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1991-03-19 US disclosed