SCHEMBL23720445

SCHEMBL23720445

CC(=O)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1OCOCOC(C)CC#N

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 1/20 0.49
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ PRKAG1 P54619 1/20 0.44
▸ PRKAA1 Q13131 1/20 0.44
▸ PRKAB1 Q9Y478 1/20 0.44
▸ ADORA2A P29274 1/20 0.44
▸ ADORA2B P29275 1/20 0.44
▸ ADORA1 P30542 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727515 0.87 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL19981006 0.87 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL20215742 0.87 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL15850629 0.87 SLC29A1 (0.51) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL17853313 0.81 PRMT5 (0.44) SLC29A1MEN1KMT2A
SCHEMBL15892160 0.81 PRMT5 (0.44) SLC29A1MEN1KMT2A
SCHEMBL31685589 0.80 MEN1 (0.69) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL26631287 0.79 SLC29A1 (0.50) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL26631283 0.79 SLC29A1 (0.50) SLC29A1MEN1KMT2AADORA2AADORA2B
SCHEMBL30540707 0.78 SLC29A1 (0.48) SLC29A1MEN1KMT2AADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210238217-A1 AMIDITE COMPOUND AND METHOD FOR PRODUCING POLYNUCLEOTIDE USING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-08-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238217-A1 AMIDITE COMPOUND AND METHOD FOR PRODUCING POLYNUCLEOTIDE USING SAID COMPOUND RNMT, REV1, TRDMT1 SLC29A1 819/4885MEN1 447/4885KMT2A 1180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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