Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13972198 | 0.74 | KDM1A (0.30) | — | |
| SCHEMBL10816016 | 0.74 | BCL2L1 (0.42) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL8290712 | 0.74 | MEN1 (0.38) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL10816476 | 0.74 | KDM4E (0.41) | ALDH1A1 | |
| SCHEMBL19359819 | 0.74 | GABRA1 (0.39) | HTR1AADRA2ASLC6A2SLC6A4 | |
| SCHEMBL18297683 | 0.71 | — | — | |
| SCHEMBL10857685 | 0.69 | DRD2 (0.40) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL4829141 | 0.69 | MEN1 (0.39) | ALDH1A1 | |
| SCHEMBL14506054 | 0.69 | — | — | |
| SCHEMBL6586502 | 0.69 | CA2 (0.39) | HTR1AADRA2ASLC6A2SLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445343-B1 | PRODRUGS OF NH-ACIDIC COMPOUNDS | ALKERMES PHARMA IRELAND LTD (IE) | 2021-08-04 | — | — | EP | disclosed |