SCHEMBL23722009

SCHEMBL23722009

O=C(O)N1CCC(n2ccc3ccccc32)CC1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.56
SLC6A4 P31645 1/20 0.56
OPRM1 P35372 1/20 0.52
OPRD1 P41143 1/20 0.52
OPRK1 P41145 1/20 0.52
OPRL1 P41146 1/20 0.52
HTR2A P28223 1/20 0.45
HTR7 P34969 1/20 0.45
SCD O00767 3/20 0.44
NOTUM Q6P988 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
L3MBTL1 Q9Y468 3/20 0.41
L3MBTL3 Q96JM7 2/20 0.41
TP53BP1 Q12888 1/20 0.41
KMT2A Q03164 1/20 0.41
TSHR P16473 1/20 0.41
RAB9A P51151 1/20 0.41
TFPI2 P48307 1/20 0.40
NPY4R P50391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23706032 0.84 DRD2 (0.44) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL3155300 0.83 DRD2 (0.51) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL3145435 0.81 DRD2 (0.59) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL26683759 0.80 HTR1A (0.42) DRD2SLC6A4HTR7SCDL3MBTL1
SCHEMBL4988197 0.80 SCD (0.47) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL4991364 0.80 HRH3 (0.47) DRD2SLC6A4HTR2AHTR7SCD
SCHEMBL4984717 0.80 TFPI2 (0.44) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL1869414 0.80 PRKCI (0.40) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL367111 0.80 DRD2 (0.63) DRD2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL29423860 0.80 DRD2 (0.63) DRD2SLC6A4OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF BIOIMICS AB (SE) 2021-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210246115-A1 ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF FDPS, FPR1, F12 DRD2 3945/4885SLC6A4 4834/4885OPRM1 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.