Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL81552 | 0.96 | S100B (0.53) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| Oxalic Acid SCHEMBL238206 | 0.86 | S100B (0.45) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL5007900 | 0.86 | GRK6 (0.48) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL11520124 | 0.86 | GRK6 (0.48) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6373886 | 0.85 | S100B (0.55) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL12907121 | 0.83 | S100B (0.52) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL237533 | 0.83 | S100B (0.45) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL80268 | 0.82 | MAPT (0.58) | S100BTERTALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL5555831 | 0.82 | S100B (0.44) | S100BTERTALDH1A1L3MBTL1HSD17B10 | |
| SCHEMBL81551 | 0.81 | S100B (0.58) | S100BTERTALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104656372-B | Imaging particle compositions, paper and method and the use dual wavelength light method to paper imaging | 国际纸业公司 | 2016-08-24 | — | — | CN | disclosed |
| EP-2541322-B1 | Composition, process of preparation and method of application and exposure for light imaging paper | INT PAPER CO (US) | 2015-08-12 | — | — | EP | disclosed |
| EP-2899592-A1 | Coated substrate comprising a dual wavelength image-forming particulate composition and a process for making said composition | INTERNATIONAL PAPER COMPANY (US) | 2015-07-29 | — | — | EP | disclosed |
| US-20150185608-A1 | IMAGING PARTICULATES, PAPER AND PROCESS, AND IMAGING OF PAPER USING DUAL WAVELENGTH LIGHT | INTERNATIONAL PAPER COMPANY | 2015-07-02 | — | — | US | disclosed |
| CN-104656372-A | Imaging particulate composition, paper and process, and imaging of paper using dual wavelength light | INT PAPER CO | 2015-05-27 | — | — | CN | disclosed |
| US-8980523-B2 | Imaging particulates, paper and process, and imaging of paper using dual wavelength light | INTERNATIONAL PAPER COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| CN-102224460-B | Imaging particulate composition, paper and method for imaging paper using dual wavelength light | INT PAPER CO | 2015-01-21 | — | — | CN | disclosed |
| EP-2340463-B1 | IMAGING PARTICULATE COMPOSITION AND IMAGING PROCESS USING DUAL WAVELENGTH LIGHT | INT PAPER CO (US) | 2014-12-17 | — | — | EP | disclosed |
| US-20140080044-A1 | Imaging Particulates, Paper and Process, and Imaging of Paper Using Dual Wavelength Light | INTERNATIONAL PAPER COMAPNY (US) | 2014-03-20 | — | — | US | disclosed |
| US-20140080057-A1 | Composition, process of preparation and method of application and exposure for light imaging paper | INTERNATIONAL PAPER COMAPNY (US) | 2014-03-20 | — | — | US | disclosed |
| EP-0066870-B1 | PHOTOIMAGING COMPOSITIONS CONTAINING SUBSTITUTED CYCLOHEXADIENONE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0024629-B1 | PHOTOIMAGING COMPOSITION COMPRISING A 2,4,5-TRIPHENYLIMIDAZOLYL DIMER AND AT LEAST ONE COMPOUND SELECTED FROM THE GROUP CONSISTING OF A LEUCO DYE AND A POLYMERIZABLE ETHYLENICALLY UNSATURATED MONOMER | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-04 | — | — | EP | disclosed |
| EP-0046271-B1 | PHOTOSENSITIVE COMPOSITIONS AND ELEMENTS CONTAINING SUBSTITUTED HYDROXYLAMINE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-10-19 | — | — | EP | disclosed |
| EP-0066870-A2 | Photoimaging compositions containing substituted cyclohexadienone compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4341860-A | A P-DI-OR TRICHLOROCYCLOHEXADIENONE OXIDIZER AND A LEUCO DYE OR UNSATURATED MONOMER; PHOTORESISTS; PHOTOPRINTOUT ELEMENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-27 | — | — | US | disclosed |
| EP-0046271-A1 | Photosensitive compositions and elements containing substituted hydroxylamine | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-02-24 | — | — | EP | disclosed |
| US-4311783-A | Dimers derived from unsymmetrical 2,4,5,-triphenylimidazole compounds as photoinitiators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4298678-A | PHOTOOXIDANT AND LEUCO DYE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-03 | — | — | US | disclosed |
| EP-0024629-A2 | Photoimaging composition comprising a 2,4,5-triphenylimidazolyl dimer and at least one compound selected from the group consisting of a leuco dye and a polymerizable ethylenically unsaturated monomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-11 | — | — | EP | disclosed |
| US-4252887-A | HIGH SPEED IMAGING; PHOTOSENSITIVE TO LONGER WAVELENGTHS; USED WITH PHOTOPOLYMERIZABLE OLEFIN; OVERLAY FILMS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |