SCHEMBL80268

SCHEMBL80268

CCN(CC)c1ccc(C)c(C(c2cc(N(CC)CC)ccc2C)c2ccccc2Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
HTT P42858 3/20 0.58
MCL1 Q07820 2/20 0.58
GAA P10253 1/20 0.58
PKM P14618 1/20 0.58
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
S1PR1 P21453 6/20 0.42
S100B P04271 1/20 0.41
GFER P55789 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TDP1 Q9NUW8 4/20 0.37
KDM4E B2RXH2 3/20 0.37
CYP3A4 P08684 2/20 0.37
HPGD P15428 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80267 0.88 MAPT (0.73) MAPTHTTMCL1GAAPKM
SCHEMBL81552 0.86 S100B (0.53) MAPTHTTMCL1GAAPKM
SCHEMBL11323425 0.85 MAPT (0.58) MAPTHTTMCL1GAAPKM
Hydrochloric Acid SCHEMBL237232 0.82 S100B (0.50) MAPTHTTMCL1GAAPKM
SCHEMBL237533 0.80 S100B (0.45) MAPTHTTGAAMEN1KMT2A
SCHEMBL5554796 0.80 MEN1 (0.40) MAPTHTTMCL1GAAPKM
SCHEMBL5010119 0.80 S100B (0.40) MAPTHTTMCL1GAAPKM
SCHEMBL5009571 0.79 MAPT (0.64) MAPTHTTMCL1GAAPKM
SCHEMBL5010064 0.78 KMT2A (0.47) MAPTHTTMCL1GAAPKM
SCHEMBL5097347 0.78 LMNA (0.49) MAPTHTTGAAPKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1705007-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2012-06-06 EP disclosed
US-8127675-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20100005989-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING METHOD FUJIFILM CORPORATION 2010-01-14 US disclosed
US-20080311524-A1 Method For Making Negative-Working Heat-Sensitive Lithographic Printing Plate Precursor AGFA GRAPHICS N.V. (BE) 2008-12-18 US disclosed
EP-1557262-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2007-11-14 EP disclosed
US-20070092836-A1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-04-26 US disclosed
EP-1717024-A1 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2006-11-02 EP disclosed
US-20060216642-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-09-28 US disclosed
EP-1705007-A2 Lithographic printing plate precursor and lithographic printing method Fuji Photo Film Co., Ltd. (JP) 2006-09-27 EP disclosed
US-20060078802-A1 Holographic storage medium SABIC INNOVATIVE PLASTICS IP B.V. 2006-04-13 US disclosed
US-20050170282-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2005-08-04 US disclosed
EP-1557262-A2 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2005-07-27 EP disclosed
EP-0239868-B1 PHOTOCHROMIC SYSTEM, LAYER PREPARED THEREOF AND ITS USE BASF Aktiengesellschaft (DE) 1989-12-27 EP disclosed
US-4857438-A Photochromic system and layers produced therewith BASF AKTIENGESELLSCHAFT (DE) 1989-08-15 US disclosed
EP-0239868-A1 Photochromic system, layer prepared thereof and its use BASF Aktiengesellschaft (DE) 1987-10-07 EP disclosed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4251619-A Process for forming photo-polymeric image KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-02-17 US disclosed