Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213200 | 0.87 | CHKA (0.55) | CHKAALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL14114972 | 0.87 | CYP2A6 (0.50) | ALDH1A1KDM4EHPGDALOX15HSD17B10 | |
| Ethane SCHEMBL6986774 | 0.85 | CHKA (0.53) | CHKAALDH1A1KDM4EHPGDALOX15 | |
| Hydrochloric Acid SCHEMBL6414496 | 0.85 | CHKA (0.53) | CHKAALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL14059916 | 0.80 | CYP2A6 (0.42) | ALDH1A1KDM4EHPGDALOX15HSD17B10 | |
| SCHEMBL21632449 | 0.80 | CYP2A6 (0.42) | ALDH1A1KDM4EHPGDALOX15HSD17B10 | |
| SCHEMBL197605 | 0.79 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL10839178 | 0.79 | CYP2A6 (0.61) | ALDH1A1ALOX15CYP2A6LMNATDP1 | |
| SCHEMBL1134844 | 0.78 | GSK3B (0.50) | CHKAALDH1A1KDM4EHPGDALOX15 | |
| SCHEMBL3181372 | 0.78 | CES2 (0.49) | CHKAALDH1A1KDM4EHPGDCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | BIOLIPOX AB (SW) | 2012-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004244-A1 | Bis Aromatic Compounds for Use as LTC4 Synthase Inhibitors | LTC4S, LTB4R2, LTB4R | CHKA 3910/4885ALDH1A1 433/4885KDM4E 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.