Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | LTA4H | P09960 | 3/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23724087 | 0.89 | MAPT (0.54) | CACNA1BMAPTLTA4HFAAHALDH1A1 | |
| SCHEMBL7043443 | 0.85 | ALDH1A1 (0.69) | CACNA1BMAPTLTA4HRAB9AALDH1A1 | |
| SCHEMBL12614692 | 0.84 | LTA4H (0.55) | MAPTLTA4HRAB9ALMNANPC1 | |
| Hydrochloric Acid SCHEMBL27903791 | 0.82 | LTA4H (0.54) | MAPTLTA4HRAB9ALMNANPC1 | |
| SCHEMBL14783746 | 0.82 | CACNA1B (0.46) | CACNA1BMAPTLTA4HFAAHRAB9A | |
| SCHEMBL7040409 | 0.82 | CACNA1B (0.71) | CACNA1BMAPTLTA4H | |
| SCHEMBL7351809 | 0.81 | CACNA1B (0.58) | CACNA1BMAPTLTA4HFAAHRAB9A | |
| SCHEMBL3801054 | 0.81 | SPR (0.50) | MAPTRAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL12813411 | 0.81 | TP53 (0.51) | MAPTRAB9AALDH1A1LMNANPC1 | |
| SCHEMBL19610351 | 0.81 | FAAH (0.52) | MAPTFAAHRAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100400-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | Kings College London (GB) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021156636-A1 | TRIAZOLE DERIVATIVES WITH ANTIFUNGAL ACTIVITY | KING'S COLLEGE LONDON (GB) | 2021-08-12 | — | — | WO | disclosed |